BDBM50108793 7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18-diazahexacyclo[9.9.1.01,9.02,17.04,8.015,21]henicosa-4(8),5,11,13,15(21)-pentaen-2-ol::CHEMBL356186

SMILES: COc1ccc2CC3N(C)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c(cn1Cc1ccccc1)-c1ccccc1

InChI Key: InChIKey=KBKTWSOCLDXSQT-OSLYBJCVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50108793 (7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18...) Show SMILES COc1ccc2CC3N(C)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c(cn1Cc1ccccc1)-c1ccccc1 |TLB:4:5:20:8.11.10,15:16:20:8.11.10| Show InChI InChI=1S/C33H32N2O3/c1-34-16-15-32-28-23-13-14-26(37-2)30(28)38-31(32)29-24(18-33(32,36)27(34)17-23)25(22-11-7-4-8-12-22)20-35(29)19-21-9-5-3-6-10-21/h3-14,20,27,31,36H,15-19H2,1-2H3/t27?,31-,32-,33+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	322	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)				J Med Chem 45: 537-40 (2002) BindingDB Entry DOI: 10.7270/Q2668DXN
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50108793 (7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18...) Show SMILES COc1ccc2CC3N(C)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c(cn1Cc1ccccc1)-c1ccccc1 |TLB:4:5:20:8.11.10,15:16:20:8.11.10| Show InChI InChI=1S/C33H32N2O3/c1-34-16-15-32-28-23-13-14-26(37-2)30(28)38-31(32)29-24(18-33(32,36)27(34)17-23)25(22-11-7-4-8-12-22)20-35(29)19-21-9-5-3-6-10-21/h3-14,20,27,31,36H,15-19H2,1-2H3/t27?,31-,32-,33+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1				J Med Chem 45: 537-40 (2002) BindingDB Entry DOI: 10.7270/Q2668DXN
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50108793 (7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18...) Show SMILES COc1ccc2CC3N(C)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c(cn1Cc1ccccc1)-c1ccccc1 |TLB:4:5:20:8.11.10,15:16:20:8.11.10| Show InChI InChI=1S/C33H32N2O3/c1-34-16-15-32-28-23-13-14-26(37-2)30(28)38-31(32)29-24(18-33(32,36)27(34)17-23)25(22-11-7-4-8-12-22)20-35(29)19-21-9-5-3-6-10-21/h3-14,20,27,31,36H,15-19H2,1-2H3/t27?,31-,32-,33+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593				J Med Chem 45: 537-40 (2002) BindingDB Entry DOI: 10.7270/Q2668DXN
					More data for this Ligand-Target Pair