BDBM50109155 2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric acid::2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic acid::CHEMBL120534
SMILES: NC(CC(O)c1cccc(O)c1)C(O)=O
InChI Key: InChIKey=APPLEPDDBNLZPX-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynureninase (Homo sapiens (Human)) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibition of human kynureninase | J Med Chem 52: 389-96 (2009) Article DOI: 10.1021/jm8010806 BindingDB Entry DOI: 10.7270/Q2DZ0860 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of St Andrews Curated by ChEMBL | Assay Description Tested for binding affinity of the compound against kynureninase enzyme from human | Bioorg Med Chem Lett 12: 361-3 (2002) BindingDB Entry DOI: 10.7270/Q2P26XFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Rattus norvegicus) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of St Andrews Curated by ChEMBL | Assay Description Tested for binding affinity of the compound against kynureninase enzyme from rat | Bioorg Med Chem Lett 12: 361-3 (2002) BindingDB Entry DOI: 10.7270/Q2P26XFS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynureninase (Homo sapiens (Human)) | BDBM50109155 (2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of St Andrews Curated by ChEMBL | Assay Description Tested for binding affinity of the compound against kynureninase enzyme from bacterial cells | Bioorg Med Chem Lett 12: 361-3 (2002) BindingDB Entry DOI: 10.7270/Q2P26XFS | |||||||||||
More data for this Ligand-Target Pair |