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SMILES: FC(F)(F)c1ccc(CNC(=O)c2ccc(NC(=O)c3cccc(CN4[C@@H](Cc5ccccc5)COC4=O)c3)cc2)cc1

InChI Key: InChIKey=TYIAGOIUAXCVPG-LJAQVGFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109165   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50109165
PNG
(CHEMBL3601094)
Show SMILES FC(F)(F)c1ccc(CNC(=O)c2ccc(NC(=O)c3cccc(CN4[C@@H](Cc5ccccc5)COC4=O)c3)cc2)cc1 |r|
Show InChI InChI=1S/C33H28F3N3O4/c34-33(35,36)27-13-9-23(10-14-27)19-37-30(40)25-11-15-28(16-12-25)38-31(41)26-8-4-7-24(17-26)20-39-29(21-43-32(39)42)18-22-5-2-1-3-6-22/h1-17,29H,18-21H2,(H,37,40)(H,38,41)/t29-/m0/s1
PDB

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a>1n/an/an/an/a



IQM-CSIC

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha transfected in human MCF7 cells after 16 hrs by luciferase reporter gene assay

J Med Chem 58: 6639-52 (2015)


BindingDB Entry DOI: 10.7270/Q29025KV
More data for this
Ligand-Target Pair