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BDBM50109178 2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperidin-1-yl)-propyl]-ureido}-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester::CHEMBL341329

SMILES: CCOC(=O)C1=C(C)N=C(C)C(C1c1cccc(NC(=O)NCCCN2CCC(CC2)c2ccccc2)c1)C(=O)OC

InChI Key: InChIKey=QLUFEWPUVVHXBV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109178   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50109178
PNG
(2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperidin-1-yl)-...)
Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1c1cccc(NC(=O)NCCCN2CCC(CC2)c2ccccc2)c1)C(=O)OC |c:5,t:8|
Show InChI InChI=1S/C33H42N4O5/c1-5-42-32(39)29-23(3)35-22(2)28(31(38)41-4)30(29)26-13-9-14-27(21-26)36-33(40)34-17-10-18-37-19-15-25(16-20-37)24-11-7-6-8-12-24/h6-9,11-14,21,25,28,30H,5,10,15-20H2,1-4H3,(H2,34,36,40)
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PubMed
 89n/an/an/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membrane

Bioorg Med Chem Lett 12: 379-82 (2002)


BindingDB Entry DOI: 10.7270/Q2DJ5DZ8
More data for this
Ligand-Target Pair