BDBM50109377 4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL147427

SMILES: COc1ccc(cc1OC)-c1csc(n1)-c1cc(sc1SC)C(N)=N

InChI Key: InChIKey=OKVKLZPKRNEJKI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50109377 (4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methyl...) Show SMILES COc1ccc(cc1OC)-c1csc(n1)-c1cc(sc1SC)C(N)=N Show InChI InChI=1S/C17H17N3O2S3/c1-21-12-5-4-9(6-13(12)22-2)11-8-24-16(20-11)10-7-14(15(18)19)25-17(10)23-3/h4-8H,1-3H3,(H3,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of Human kidney cell urokinase				Bioorg Med Chem Lett 12: 491-5 (2002) BindingDB Entry DOI: 10.7270/Q2H994H5
					More data for this Ligand-Target Pair