BDBM50109377 4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL147427
SMILES: COc1ccc(cc1OC)-c1csc(n1)-c1cc(sc1SC)C(N)=N
InChI Key: InChIKey=OKVKLZPKRNEJKI-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50109377 (4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
3-Dimensional Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of Human kidney cell urokinase | Bioorg Med Chem Lett 12: 491-5 (2002) BindingDB Entry DOI: 10.7270/Q2H994H5 | |||||||||||
More data for this Ligand-Target Pair |