BDBM50109397 CHEMBL3601222

SMILES: COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)c1cccc2c(cccc12)N(CC(O)=O)S(=O)(=O)c1ccc(OC)cc1

InChI Key: InChIKey=YSAPXQGVGMWUDJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50109397 (CHEMBL3601222) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)c1cccc2c(cccc12)N(CC(O)=O)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C28H26N2O10S2/c1-39-19-9-13-21(14-10-19)41(35,36)29(17-27(31)32)25-7-3-6-24-23(25)5-4-8-26(24)30(18-28(33)34)42(37,38)22-15-11-20(40-2)12-16-22/h3-16H,17-18H2,1-2H3,(H,31,32)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...				J Med Chem 58: 6410-21 (2015) BindingDB Entry DOI: 10.7270/Q2CR5W5H
					More data for this Ligand-Target Pair