BDBM50109568 CHEMBL3604132

SMILES: Fc1ccc(NC(=O)c2cc[nH]n2)c(Cl)c1

InChI Key: InChIKey=PDLYRDKUJZKLJN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50109568 (CHEMBL3604132) Show SMILES Fc1ccc(NC(=O)c2cc[nH]n2)c(Cl)c1 Show InChI InChI=1S/C10H7ClFN3O/c11-7-5-6(12)1-2-8(7)14-10(16)9-3-4-13-15-9/h1-5H,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...				Bioorg Med Chem Lett 25: 3024-9 (2015) BindingDB Entry DOI: 10.7270/Q2R21350
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50109568 (CHEMBL3604132) Show SMILES Fc1ccc(NC(=O)c2cc[nH]n2)c(Cl)c1 Show InChI InChI=1S/C10H7ClFN3O/c11-7-5-6(12)1-2-8(7)14-10(16)9-3-4-13-15-9/h1-5H,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...				Bioorg Med Chem Lett 25: 3024-9 (2015) BindingDB Entry DOI: 10.7270/Q2R21350
					More data for this Ligand-Target Pair