null

SMILES: CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1

InChI Key: InChIKey=XRIFBRFEZLXEFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50109623 ((4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1...) Show SMILES CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1 Show InChI InChI=1S/C18H22N3O4P/c1-2-25-26(24,16-9-7-15(19)8-10-16)21-12-14-6-4-3-5-13(14)11-17(21)18(22)20-23/h3-10,17,23H,2,11-12,19H2,1H3,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50109623 ((4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1...) Show SMILES CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1 Show InChI InChI=1S/C18H22N3O4P/c1-2-25-26(24,16-9-7-15(19)8-10-16)21-12-14-6-4-3-5-13(14)11-17(21)18(22)20-23/h3-10,17,23H,2,11-12,19H2,1H3,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9 (Homo sapiens (Human))	BDBM50109623 ((4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1...) Show SMILES CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1 Show InChI InChI=1S/C18H22N3O4P/c1-2-25-26(24,16-9-7-15(19)8-10-16)21-12-14-6-4-3-5-13(14)11-17(21)18(22)20-23/h3-10,17,23H,2,11-12,19H2,1H3,(H,20,22)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50109623 ((4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1...) Show SMILES CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1 Show InChI InChI=1S/C18H22N3O4P/c1-2-25-26(24,16-9-7-15(19)8-10-16)21-12-14-6-4-3-5-13(14)11-17(21)18(22)20-23/h3-10,17,23H,2,11-12,19H2,1H3,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	75.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50109623 ((4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1...) Show SMILES CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1 Show InChI InChI=1S/C18H22N3O4P/c1-2-25-26(24,16-9-7-15(19)8-10-16)21-12-14-6-4-3-5-13(14)11-17(21)18(22)20-23/h3-10,17,23H,2,11-12,19H2,1H3,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	95.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair