BDBM50109660 4'-Pyrimidin-4-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL346862

SMILES: Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccncn2)c1C

InChI Key: InChIKey=OXPDZJBNFCQMDY-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50109660 (4'-Pyrimidin-4-yl-biphenyl-2-sulfonic acid (3,4-di...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccncn2)c1C Show InChI InChI=1S/C21H18N4O3S/c1-14-15(2)24-28-21(14)25-29(26,27)20-6-4-3-5-18(20)16-7-9-17(10-8-16)19-11-12-22-13-23-19/h3-13,25H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin A receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50109660 (4'-Pyrimidin-4-yl-biphenyl-2-sulfonic acid (3,4-di...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccncn2)c1C Show InChI InChI=1S/C21H18N4O3S/c1-14-15(2)24-28-21(14)25-29(26,27)20-6-4-3-5-18(20)16-7-9-17(10-8-16)19-11-12-22-13-23-19/h3-13,25H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin B receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair