BDBM50109662 4'-(1-Oxy-pyridin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL147238

SMILES: Cc1[n-][o+]c(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cccc[n+]2[O-])c1C

InChI Key: InChIKey=AITOTEQUPDSIJB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50109662 (4'-(1-Oxy-pyridin-2-yl)-biphenyl-2-sulfonic acid (...) Show SMILES Cc1[n-][o+]c(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cccc[n+]2[O-])c1C Show InChI InChI=1S/C22H19N3O4S/c1-15-16(2)23-29-22(15)24-30(27,28)21-9-4-3-7-19(21)17-10-12-18(13-11-17)20-8-5-6-14-25(20)26/h3-14,24H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin A receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50109662 (4'-(1-Oxy-pyridin-2-yl)-biphenyl-2-sulfonic acid (...) Show SMILES Cc1[n-][o+]c(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cccc[n+]2[O-])c1C Show InChI InChI=1S/C22H19N3O4S/c1-15-16(2)23-29-22(15)24-30(27,28)21-9-4-3-7-19(21)17-10-12-18(13-11-17)20-8-5-6-14-25(20)26/h3-14,24H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.08E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin B receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair