BDBM50109825 CHEMBL1288905

SMILES: Brc1ccc(cc1)-c1c[nH]c(n1)-c1ccccc1C#N

InChI Key: InChIKey=AEOKACDFDSLENU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50109825 (CHEMBL1288905) Show SMILES Brc1ccc(cc1)-c1c[nH]c(n1)-c1ccccc1C#N Show InChI InChI=1S/C16H10BrN3/c17-13-7-5-11(6-8-13)15-10-19-16(20-15)14-4-2-1-3-12(14)9-18/h1-8,10H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of mPGES-1 in IL-1beta-stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 formation incubated for 15 mins using...				Bioorg Med Chem 23: 4839-45 (2015) BindingDB Entry DOI: 10.7270/Q2M90BF8
					More data for this Ligand-Target Pair