BDBM50110039 1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propyl]-1,3-dihydro-imidazol-2-one::CHEMBL434092

SMILES: COc1ccc(cc1OCC1CC1)C(C)Cn1cc[nH]c1=O

InChI Key: InChIKey=ACBYRQONKZKIIY-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (RAT-Rattus norvegicus)	BDBM50110039 (1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...) Show SMILES COc1ccc(cc1OCC1CC1)C(C)Cn1cc[nH]c1=O Show InChI InChI=1S/C17H22N2O3/c1-12(10-19-8-7-18-17(19)20)14-5-6-15(21-2)16(9-14)22-11-13-3-4-13/h5-9,12-13H,3-4,10-11H2,1-2H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Displacement of [3H]rolipram from rat forebrain membrane				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50110039 (1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...) Show SMILES COc1ccc(cc1OCC1CC1)C(C)Cn1cc[nH]c1=O Show InChI InChI=1S/C17H22N2O3/c1-12(10-19-8-7-18-17(19)20)14-5-6-15(21-2)16(9-14)22-11-13-3-4-13/h5-9,12-13H,3-4,10-11H2,1-2H3,(H,18,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair