BDBM50110298 CHEMBL277113::Ethyl-(3-piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxalic acid

SMILES: CCN(CCCN1CCCCC1)c1ccnc2ccccc12

InChI Key: InChIKey=IHXVMTQOYIUZHB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50110298 (CHEMBL277113 | Ethyl-(3-piperidin-1-yl-propyl)-qui...) Show SMILES CCN(CCCN1CCCCC1)c1ccnc2ccccc12 Show InChI InChI=1S/C19H27N3/c1-2-22(16-8-15-21-13-6-3-7-14-21)19-11-12-20-18-10-5-4-9-17(18)19/h4-5,9-12H,2-3,6-8,13-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cells				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110298 (CHEMBL277113 | Ethyl-(3-piperidin-1-yl-propyl)-qui...) Show SMILES CCN(CCCN1CCCCC1)c1ccnc2ccccc12 Show InChI InChI=1S/C19H27N3/c1-2-22(16-8-15-21-13-6-3-7-14-21)19-11-12-20-18-10-5-4-9-17(18)19/h4-5,9-12H,2-3,6-8,13-16H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair