BDBM50110308 (7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-ethyl}-amine; Oxalic acid::CHEMBL14587

SMILES: Clc1ccc2c(NCCc3ccc(OCCCN4CCCCC4)cc3)ccnc2c1

InChI Key: InChIKey=KFFMRYQMDWYABB-UHFFFAOYSA-N

Data: 1 IC50  3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50110308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110308 ((7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-p...) Show SMILES Clc1ccc2c(NCCc3ccc(OCCCN4CCCCC4)cc3)ccnc2c1 Show InChI InChI=1S/C25H30ClN3O/c26-21-7-10-23-24(12-14-28-25(23)19-21)27-13-11-20-5-8-22(9-6-20)30-18-4-17-29-15-2-1-3-16-29/h5-10,12,14,19H,1-4,11,13,15-18H2,(H,27,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50110308 ((7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-p...) Show SMILES Clc1ccc2c(NCCc3ccc(OCCCN4CCCCC4)cc3)ccnc2c1 Show InChI InChI=1S/C25H30ClN3O/c26-21-7-10-23-24(12-14-28-25(23)19-21)27-13-11-20-5-8-22(9-6-20)30-18-4-17-29-15-2-1-3-16-29/h5-10,12,14,19H,1-4,11,13,15-18H2,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Activity at Histamine H1 receptor using functional H1 receptor assay on guinea pig ileum				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50110308 ((7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-p...) Show SMILES Clc1ccc2c(NCCc3ccc(OCCCN4CCCCC4)cc3)ccnc2c1 Show InChI InChI=1S/C25H30ClN3O/c26-21-7-10-23-24(12-14-28-25(23)19-21)27-13-11-20-5-8-22(9-6-20)30-18-4-17-29-15-2-1-3-16-29/h5-10,12,14,19H,1-4,11,13,15-18H2,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Activity at Histamine H3 receptor using functional H3 receptor assay on guinea pig ileum				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50110308 ((7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-p...) Show SMILES Clc1ccc2c(NCCc3ccc(OCCCN4CCCCC4)cc3)ccnc2c1 Show InChI InChI=1S/C25H30ClN3O/c26-21-7-10-23-24(12-14-28-25(23)19-21)27-13-11-20-5-8-22(9-6-20)30-18-4-17-29-15-2-1-3-16-29/h5-10,12,14,19H,1-4,11,13,15-18H2,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Activity at Histamine H2 receptor using functional H2 receptor assay on guinea pig atrium				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair