BDBM50110310 (3-Methyl-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-amine; Oxalic acid::CHEMBL14595

SMILES: Cc1cnc2ccccc2c1NCCCCCCN1CCCCC1

InChI Key: InChIKey=DDWXFEAPUBSMTJ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50110310 ((3-Methyl-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...) Show SMILES Cc1cnc2ccccc2c1NCCCCCCN1CCCCC1 Show InChI InChI=1S/C21H31N3/c1-18-17-23-20-12-6-5-11-19(20)21(18)22-13-7-2-3-8-14-24-15-9-4-10-16-24/h5-6,11-12,17H,2-4,7-10,13-16H2,1H3,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cells				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110310 ((3-Methyl-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...) Show SMILES Cc1cnc2ccccc2c1NCCCCCCN1CCCCC1 Show InChI InChI=1S/C21H31N3/c1-18-17-23-20-12-6-5-11-19(20)21(18)22-13-7-2-3-8-14-24-15-9-4-10-16-24/h5-6,11-12,17H,2-4,7-10,13-16H2,1H3,(H,22,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair