BDBM50110474 CHEMBL3605802
SMILES: COc1ccc(CNC2(CCCC2)c2nc(c[nH]2)-c2ccc(C)cc2)cc1
InChI Key: InChIKey=WMWUQTXOEORCTN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50110474 (CHEMBL3605802) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins | Bioorg Med Chem Lett 25: 3520-5 (2015) BindingDB Entry DOI: 10.7270/Q29W0H9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50110474 (CHEMBL3605802) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 96 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay | Bioorg Med Chem Lett 25: 3520-5 (2015) BindingDB Entry DOI: 10.7270/Q29W0H9M | |||||||||||
More data for this Ligand-Target Pair |