BDBM50110518 CHEMBL3605835

SMILES: CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(F)cc2)cc1

InChI Key: InChIKey=XTJMRCLOINUNKE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM50110518 (CHEMBL3605835) Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H31FN2O2S/c1-27(2,3)23-7-4-20(5-8-23)14-16-30-17-15-21-18-26(13-6-22(21)19-30)33(31,32)29-25-11-9-24(28)10-12-25/h4-13,18,29H,14-17,19H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...				Bioorg Med Chem 23: 5922-31 (2015) BindingDB Entry DOI: 10.7270/Q2639RJ6
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Mus musculus)	BDBM50110518 (CHEMBL3605835) Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H31FN2O2S/c1-27(2,3)23-7-4-20(5-8-23)14-16-30-17-15-21-18-26(13-6-22(21)19-30)33(31,32)29-25-11-9-24(28)10-12-25/h4-13,18,29H,14-17,19H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of mouse recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...				Bioorg Med Chem 23: 5922-31 (2015) BindingDB Entry DOI: 10.7270/Q2639RJ6
					More data for this Ligand-Target Pair