BDBM50110589 CHEMBL3605833

SMILES: CC(C)(C)c1ccc(CCN2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(F)cc2)cc1

InChI Key: InChIKey=DMFOIHXHPDSGEJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM50110589 (CHEMBL3605833) Show SMILES CC(C)(C)c1ccc(CCN2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C26H29FN2O2S/c1-26(2,3)22-7-4-19(5-8-22)14-15-29-17-20-6-13-25(16-21(20)18-29)32(30,31)28-24-11-9-23(27)10-12-24/h4-13,16,28H,14-15,17-18H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...				Bioorg Med Chem 23: 5922-31 (2015) BindingDB Entry DOI: 10.7270/Q2639RJ6
					More data for this Ligand-Target Pair