new BindingDB logo
myBDB logout

BDBM50110678 CHEMBL3605830

SMILES: CCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1

InChI Key: InChIKey=OYROAJMRGLCXAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110678   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM50110678
PNG
(CHEMBL3605830)
Show SMILES CCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1
Show InChI InChI=1S/C29H34FN3O4S/c1-5-6-15-37-24-12-14-27(26(30)17-24)32-38(35,36)25-13-7-20-18-33(19-21(20)16-25)28(34)31-23-10-8-22(9-11-23)29(2,3)4/h7-14,16-17,32H,5-6,15,18-19H2,1-4H3,(H,31,34)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 547n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...


Bioorg Med Chem 23: 5922-31 (2015)


BindingDB Entry DOI: 10.7270/Q2639RJ6
More data for this
Ligand-Target Pair