BDBM50110690 CHEMBL17377::FOSTRIECIN::Phosphoric acid mono-{3,10-dihydroxy-1-[1-hydroxy-1-methyl-3-(6-oxo-3,6-dihydro-2H-pyran-2-yl)-allyl]-deca-4,6,8-trienyl} ester

SMILES: C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O

InChI Key: InChIKey=ZMQRJWIYMXZORG-DSWNLJKISA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2 (Drosophila melanogaster)	BDBM50110690 (CHEMBL17377 | FOSTRIECIN | Phosphoric acid mono-{3...) Show SMILES C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O |c:7| Show InChI InChI=1S/C19H27O9P/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26)/b3-2-,6-4+,8-5-,12-11+/t15-,16+,17+,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of topoisomerase IIin vitro through a novel, non-DNA-strandcleaving mechanism				Bioorg Med Chem Lett 10: 1687-90 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6Z8N
					More data for this Ligand-Target Pair
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus)	BDBM50110690 (CHEMBL17377 | FOSTRIECIN | Phosphoric acid mono-{3...) Show SMILES C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O |c:7| Show InChI InChI=1S/C19H27O9P/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26)/b3-2-,6-4+,8-5-,12-11+/t15-,16+,17+,19+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)				J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG
					More data for this Ligand-Target Pair
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus)	BDBM50110690 (CHEMBL17377 | FOSTRIECIN | Phosphoric acid mono-{3...) Show SMILES C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O |c:7| Show InChI InChI=1S/C19H27O9P/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26)/b3-2-,6-4+,8-5-,12-11+/t15-,16+,17+,19+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against partially purified (chicken skeletal muscle) Protein phosphatase 2A				Bioorg Med Chem Lett 10: 1687-90 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6Z8N
					More data for this Ligand-Target Pair