BDBM50110715 5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-butoxy)-phenyl]-oxazolidin-2-one::CHEMBL18101

SMILES: COC[C@@H]1CN(C(=O)O1)c1ccc(OCC[C@H](O)C(F)(F)F)cc1

InChI Key: InChIKey=IALVDLPLCLFBCF-STQMWFEESA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Bos taurus)	BDBM50110715 (5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-bu...) Show SMILES COC[C@@H]1CN(C(=O)O1)c1ccc(OCC[C@H](O)C(F)(F)F)cc1 Show InChI InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial Monoamine oxidase A (MAO-A) compared to toloxatone				J Med Chem 45: 1180-3 (2002) BindingDB Entry DOI: 10.7270/Q28W3F11
					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50110715 (5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-bu...) Show SMILES COC[C@@H]1CN(C(=O)O1)c1ccc(OCC[C@H](O)C(F)(F)F)cc1 Show InChI InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial Monoamine oxidase B (MAO-B) compared to toloxatone				J Med Chem 45: 1180-3 (2002) BindingDB Entry DOI: 10.7270/Q28W3F11
					More data for this Ligand-Target Pair