null

SMILES: COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12

InChI Key: InChIKey=XCCRMYVOJIFMED-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50110734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50110734 (CHEMBL3605930) Show SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12 Show InChI InChI=1S/C16H15ClN2O3S/c1-22-15-7-6-10(17)8-12(15)13-9-18-16-11(13)4-3-5-14(16)19-23(2,20)21/h3-9,18-19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly Biotechnology Center Curated by ChEMBL					Assay Description Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...				J Med Chem 58: 6607-18 (2015) BindingDB Entry DOI: 10.7270/Q2ST7RMV
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50110734 (CHEMBL3605930) Show SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12 Show InChI InChI=1S/C16H15ClN2O3S/c1-22-15-7-6-10(17)8-12(15)13-9-18-16-11(13)4-3-5-14(16)19-23(2,20)21/h3-9,18-19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	233	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly Biotechnology Center Curated by ChEMBL					Assay Description Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...				J Med Chem 58: 6607-18 (2015) BindingDB Entry DOI: 10.7270/Q2ST7RMV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50110734 (CHEMBL3605930) Show SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12 Show InChI InChI=1S/C16H15ClN2O3S/c1-22-15-7-6-10(17)8-12(15)13-9-18-16-11(13)4-3-5-14(16)19-23(2,20)21/h3-9,18-19H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	697	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly Biotechnology Center Curated by ChEMBL					Assay Description Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...				J Med Chem 58: 6607-18 (2015) BindingDB Entry DOI: 10.7270/Q2ST7RMV
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50110734 (CHEMBL3605930) Show SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12 Show InChI InChI=1S/C16H15ClN2O3S/c1-22-15-7-6-10(17)8-12(15)13-9-18-16-11(13)4-3-5-14(16)19-23(2,20)21/h3-9,18-19H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly Biotechnology Center Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competit...				J Med Chem 58: 6607-18 (2015) BindingDB Entry DOI: 10.7270/Q2ST7RMV
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50110734 (CHEMBL3605930) Show SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12 Show InChI InChI=1S/C16H15ClN2O3S/c1-22-15-7-6-10(17)8-12(15)13-9-18-16-11(13)4-3-5-14(16)19-23(2,20)21/h3-9,18-19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly Biotechnology Center Curated by ChEMBL					Assay Description Antagonist activity against glucocorticoid receptor (unknown origin) expressed in HEK293 cells by GRE-dependent luciferase reporter gene assay				J Med Chem 58: 6607-18 (2015) BindingDB Entry DOI: 10.7270/Q2ST7RMV
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50110734 (CHEMBL3605930) Show SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12 Show InChI InChI=1S/C16H15ClN2O3S/c1-22-15-7-6-10(17)8-12(15)13-9-18-16-11(13)4-3-5-14(16)19-23(2,20)21/h3-9,18-19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly Biotechnology Center Curated by ChEMBL					Assay Description Antagonist activity against glucocorticoid receptor in rat H4-IIE cells assessed as inhibition of dexamethasone-induced receptor transactivation pre-...				J Med Chem 58: 6607-18 (2015) BindingDB Entry DOI: 10.7270/Q2ST7RMV
					More data for this Ligand-Target Pair