BDBM50110782 CHEMBL429065::[5-Iodo-2-(2-methylaminomethyl-phenylsulfanyl)-phenyl]-methanol
SMILES: CNCc1ccccc1Sc1ccc(I)cc1CO
InChI Key: InChIKey=OSNXAVGNELKROQ-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50110782 (CHEMBL429065 | [5-Iodo-2-(2-methylaminomethyl-phen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membrane | J Med Chem 45: 1253-8 (2002) BindingDB Entry DOI: 10.7270/Q2TH8M15 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50110782 (CHEMBL429065 | [5-Iodo-2-(2-methylaminomethyl-phen...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibition of [3H]-nisoxatine binding to norepinephrine transporter (NET) of rat cortical homogenates | J Med Chem 45: 1253-8 (2002) BindingDB Entry DOI: 10.7270/Q2TH8M15 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50110782 (CHEMBL429065 | [5-Iodo-2-(2-methylaminomethyl-phen...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibition of [3H]-GBR-12,935 binding to dopamine transporter (DAT) of rat striatal membranes | J Med Chem 45: 1253-8 (2002) BindingDB Entry DOI: 10.7270/Q2TH8M15 | |||||||||||
More data for this Ligand-Target Pair |