BDBM50110796 (4-(6-amino-9H-purin-9-yl)cyclopent-2-enyloxy)methylphosphonic diphosphoric anhydride::9-[4-(Diphosphoryloxyphosphonylmethoxy)-cyclopent-2-enyl]adenine::CHEMBL281913

SMILES: Nc1ncnc2n(cnc12)C1CC(OCP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=C1

InChI Key: InChIKey=VUGGRZMGKXPUEU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50110796 ((4-(6-amino-9H-purin-9-yl)cyclopent-2-enyloxy)meth...) Show SMILES Nc1ncnc2n(cnc12)C1CC(OCP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=C1 |c:29| Show InChI InChI=1S/C11H16N5O10P3/c12-10-9-11(14-4-13-10)16(5-15-9)7-1-2-8(3-7)24-6-27(17,18)25-29(22,23)26-28(19,20)21/h1-2,4-5,7-8H,3,6H2,(H,17,18)(H,22,23)(H2,12,13,14)(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DNA synthesis by HIV reverse transcriptase				J Med Chem 45: 1284-91 (2002) BindingDB Entry DOI: 10.7270/Q2PR7V9F
					More data for this Ligand-Target Pair