BDBM50110805 CHEMBL3605964
SMILES: CCOCC(C(=O)c1ccc(Cl)cc1)n1cnc2ncnc(N)c12
InChI Key: InChIKey=KUAQQWXZBQXKEU-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNMT3A2/3L complex (Homo sapiens (Human)) | BDBM50110805 (CHEMBL3605964) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388 Curated by ChEMBL | Assay Description Inhibition of human C-terminal DNMT3A after 1 hr by fluorescence assay | Bioorg Med Chem 23: 5946-53 (2015) BindingDB Entry DOI: 10.7270/Q2P270X8 | |||||||||||
More data for this Ligand-Target Pair |