BDBM50110891 CHEMBL3604536
SMILES: [NH4+].[NH4+].[NH4+].[NH4+].[BH3-][P@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c[n+](C)c2c([O-])nc(N)nc12)OP([O-])(=O)OP([O-])([O-])=O
InChI Key: InChIKey=MOQDOBXLGCKHGD-PFJPIRMESA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110891 (CHEMBL3604536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l... | Bioorg Med Chem 23: 5369-81 (2015) BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus) | BDBM50110891 (CHEMBL3604536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Warsaw Curated by ChEMBL | Assay Description Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b... | Bioorg Med Chem 23: 5369-81 (2015) BindingDB Entry DOI: 10.7270/Q2DN46V3 | |||||||||||
More data for this Ligand-Target Pair |