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BDBM50111006 5-{3-[4-(2-Furan-2-yl-5-methyl-oxazol-4-ylmethoxy)-3-methoxy-phenyl]-propyl}-oxazolidine-2,4-dione::CHEMBL289272

SMILES: COc1cc(CCCc2oc(=O)[nH]c2O)ccc1OCc1nc(oc1C)-c1ccco1

InChI Key: InChIKey=HYOQMRYZQUGPRK-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111006   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome Proliferator-Activated Receptor gamma/Retinoid X receptor alpha


(Homo sapiens (Human))
BDBM50111006
PNG
(5-{3-[4-(2-Furan-2-yl-5-methyl-oxazol-4-ylmethoxy)...)
Show SMILES COc1cc(CCCc2oc(=O)[nH]c2O)ccc1OCc1nc(oc1C)-c1ccco1
Show InChI InChI=1S/C22H22N2O7/c1-13-15(23-21(30-13)18-7-4-10-28-18)12-29-16-9-8-14(11-19(16)27-2)5-3-6-17-20(25)24-22(26)31-17/h4,7-11,25H,3,5-6,12H2,1-2H3,(H,24,26)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/an/an/a 8.87n/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Transcriptional activation in COS cells expressing PPAR gamma and RXR alpha


J Med Chem 45: 1518-34 (2002)


BindingDB Entry DOI: 10.7270/Q2SJ1JXC
More data for this
Ligand-Target Pair