BDBM50111006 5-{3-[4-(2-Furan-2-yl-5-methyl-oxazol-4-ylmethoxy)-3-methoxy-phenyl]-propyl}-oxazolidine-2,4-dione::CHEMBL289272

SMILES: COc1cc(CCCc2oc(=O)[nH]c2O)ccc1OCc1nc(oc1C)-c1ccco1

InChI Key: InChIKey=HYOQMRYZQUGPRK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma/Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50111006 (5-{3-[4-(2-Furan-2-yl-5-methyl-oxazol-4-ylmethoxy)...) Show SMILES COc1cc(CCCc2oc(=O)[nH]c2O)ccc1OCc1nc(oc1C)-c1ccco1 Show InChI InChI=1S/C22H22N2O7/c1-13-15(23-21(30-13)18-7-4-10-28-18)12-29-16-9-8-14(11-19(16)27-2)5-3-6-17-20(25)24-22(26)31-17/h4,7-11,25H,3,5-6,12H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	8.87	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Transcriptional activation in COS cells expressing PPAR gamma and RXR alpha				J Med Chem 45: 1518-34 (2002) BindingDB Entry DOI: 10.7270/Q2SJ1JXC
					More data for this Ligand-Target Pair