BDBM50111008 5-{3-[4-(5-Methyl-2-phenyl-thiazol-4-ylmethoxy)-phenyl]-propyl}-oxazolidine-2,4-dione::CHEMBL37950

SMILES: Cc1sc(nc1COc1ccc(CCCc2oc(=O)[nH]c2O)cc1)-c1ccccc1

InChI Key: InChIKey=BXZHDYPSVZQZHE-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome Proliferator-Activated Receptor gamma/Retinoid X receptor alpha (Homo sapiens (Human))	BDBM50111008 (5-{3-[4-(5-Methyl-2-phenyl-thiazol-4-ylmethoxy)-ph...) Show SMILES Cc1sc(nc1COc1ccc(CCCc2oc(=O)[nH]c2O)cc1)-c1ccccc1 Show InChI InChI=1S/C23H22N2O4S/c1-15-19(24-22(30-15)17-7-3-2-4-8-17)14-28-18-12-10-16(11-13-18)6-5-9-20-21(26)25-23(27)29-20/h2-4,7-8,10-13,26H,5-6,9,14H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	269	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Transcriptional activation in COS cells expressing PPAR gamma and RXR alpha				J Med Chem 45: 1518-34 (2002) BindingDB Entry DOI: 10.7270/Q2SJ1JXC
					More data for this Ligand-Target Pair
Peroxisome Proliferator-Activated Receptor gamma/Retinoid X receptor alpha (Homo sapiens (Human))	BDBM50111008 (5-{3-[4-(5-Methyl-2-phenyl-thiazol-4-ylmethoxy)-ph...) Show SMILES Cc1sc(nc1COc1ccc(CCCc2oc(=O)[nH]c2O)cc1)-c1ccccc1 Show InChI InChI=1S/C23H22N2O4S/c1-15-19(24-22(30-15)17-7-3-2-4-8-17)14-28-18-12-10-16(11-13-18)6-5-9-20-21(26)25-23(27)29-20/h2-4,7-8,10-13,26H,5-6,9,14H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Transcriptional activation in COS cells expressing PPAR gamma and RXR alpha				J Med Chem 45: 1518-34 (2002) BindingDB Entry DOI: 10.7270/Q2SJ1JXC
					More data for this Ligand-Target Pair