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BDBM50111010 5-{3-[4-(5-Methyl-2-naphthalen-2-yl-oxazol-4-ylmethoxy)-phenyl]-propyl}-oxazolidine-2,4-dione::CHEMBL39315

SMILES: Cc1oc(nc1COc1ccc(CCCc2oc(=O)[nH]c2O)cc1)-c1ccc2ccccc2c1

InChI Key: InChIKey=VLVRARFHPMWJLF-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111010   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome Proliferator-Activated Receptor gamma/Retinoid X receptor alpha


(Homo sapiens (Human))
BDBM50111010
PNG
(5-{3-[4-(5-Methyl-2-naphthalen-2-yl-oxazol-4-ylmet...)
Show SMILES Cc1oc(nc1COc1ccc(CCCc2oc(=O)[nH]c2O)cc1)-c1ccc2ccccc2c1
Show InChI InChI=1S/C27H24N2O5/c1-17-23(28-26(33-17)21-12-11-19-6-2-3-7-20(19)15-21)16-32-22-13-9-18(10-14-22)5-4-8-24-25(30)29-27(31)34-24/h2-3,6-7,9-15,30H,4-5,8,16H2,1H3,(H,29,31)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 29.3n/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Transcriptional activation in COS cells expressing PPAR gamma and RXR alpha


J Med Chem 45: 1518-34 (2002)


BindingDB Entry DOI: 10.7270/Q2SJ1JXC
More data for this
Ligand-Target Pair