BDBM50111323 CHEMBL276202::N'-(11-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-6-yl)-N,N-dimethyl-propane-1,3-diamine

SMILES: COc1ccc2ccc3c([nH]c4c3c(NCCCN(C)C)nc3ccccc43)c2c1

InChI Key: InChIKey=PYEIRPIIHGYZAD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Taq polymerase 1 (Thermus aquaticus)	BDBM50111323 (CHEMBL276202 | N'-(11-Methoxy-13H-5,13-diaza-diben...) Show SMILES COc1ccc2ccc3c([nH]c4c3c(NCCCN(C)C)nc3ccccc43)c2c1 Show InChI InChI=1S/C25H26N4O/c1-29(2)14-6-13-26-25-22-19-12-10-16-9-11-17(30-3)15-20(16)23(19)28-24(22)18-7-4-5-8-21(18)27-25/h4-5,7-12,15,28H,6,13-14H2,1-3H3,(H,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Tested for inhibitory activity against Taq DNA polymerase				Bioorg Med Chem Lett 12: 1071-4 (2002) BindingDB Entry DOI: 10.7270/Q2RJ4HS0
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50111323 (CHEMBL276202 | N'-(11-Methoxy-13H-5,13-diaza-diben...) Show SMILES COc1ccc2ccc3c([nH]c4c3c(NCCCN(C)C)nc3ccccc43)c2c1 Show InChI InChI=1S/C25H26N4O/c1-29(2)14-6-13-26-25-22-19-12-10-16-9-11-17(30-3)15-20(16)23(19)28-24(22)18-7-4-5-8-21(18)27-25/h4-5,7-12,15,28H,6,13-14H2,1-3H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Tested for inhibitory activity against Telomerase in telomerase repeat amplification protocol (TRAP) assay				Bioorg Med Chem Lett 12: 1071-4 (2002) BindingDB Entry DOI: 10.7270/Q2RJ4HS0
					More data for this Ligand-Target Pair