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SMILES: COC(=O)CSc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3ccccc23)cc1

InChI Key: InChIKey=MAEKYLZYQYCGDV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111336   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))		BDBM50111336
PNG
(CHEMBL11892 | {4-[1'-(Naphthalene-1-carbonyl)-[1,4...)
Show SMILES COC(=O)CSc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3ccccc23)cc1
Show InChI InChI=1S/C31H36N2O3S/c1-36-30(34)22-37-27-11-9-23(10-12-27)21-24-13-17-32(18-14-24)26-15-19-33(20-16-26)31(35)29-8-4-6-25-5-2-3-7-28(25)29/h2-12,24,26H,13-22H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.700n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.

Bioorg Med Chem Lett 12: 1087-91 (2002)


BindingDB Entry DOI: 10.7270/Q2MS3S2P
More data for this
Ligand-Target Pair