BDBM50111356 CHEMBL11756::[4-(4-Isopropylsulfanyl-benzyl)-[1,4']bipiperidinyl-1'-yl]-quinolin-5-yl-methanone

SMILES: CC(C)Sc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3ncccc23)cc1

InChI Key: InChIKey=ZQIBSMJNQOCPSC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50111356 (CHEMBL11756 | [4-(4-Isopropylsulfanyl-benzyl)-[1,4...) Show SMILES CC(C)Sc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3ncccc23)cc1 Show InChI InChI=1S/C30H37N3OS/c1-22(2)35-26-10-8-23(9-11-26)21-24-12-17-32(18-13-24)25-14-19-33(20-15-25)30(34)28-5-3-7-29-27(28)6-4-16-31-29/h3-11,16,22,24-25H,12-15,17-21H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.				Bioorg Med Chem Lett 12: 1087-91 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S2P
					More data for this Ligand-Target Pair