BDBM50111402 6-Oxo-6-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-yl)-hexanoic acid::CHEMBL13033

SMILES: OC(=O)CCCCC(=O)N1CCC2(C1)CCN(CC2)c1ccncc1

InChI Key: InChIKey=LMEKJOXYAOIJFH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50111402 (6-Oxo-6-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec-2-...) Show SMILES OC(=O)CCCCC(=O)N1CCC2(C1)CCN(CC2)c1ccncc1 Show InChI InChI=1S/C19H27N3O3/c23-17(3-1-2-4-18(24)25)22-14-9-19(15-22)7-12-21(13-8-19)16-5-10-20-11-6-16/h5-6,10-11H,1-4,7-9,12-15H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.				Bioorg Med Chem Lett 12: 1103-7 (2002) BindingDB Entry DOI: 10.7270/Q2H131BN
					More data for this Ligand-Target Pair