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BDBM50111407 3-[2-Oxo-4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]decane-2-carbonyl)-piperazin-1-yl]-propionic acid::CHEMBL276405

SMILES: OC(=O)CCN1CCN(CC1=O)C(=O)N1CCC2(C1)CCN(CC2)c1ccncc1

InChI Key: InChIKey=DDXJSWMWHOOAKR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111407   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50111407
PNG
(3-[2-Oxo-4-(8-pyridin-4-yl-2,8-diaza-spiro[4.5]dec...)
Show SMILES OC(=O)CCN1CCN(CC1=O)C(=O)N1CCC2(C1)CCN(CC2)c1ccncc1
Show InChI InChI=1S/C21H29N5O4/c27-18-15-25(14-13-24(18)9-3-19(28)29)20(30)26-12-6-21(16-26)4-10-23(11-5-21)17-1-7-22-8-2-17/h1-2,7-8H,3-6,9-16H2,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 238n/an/an/an/an/an/a



COR Therapeutics, Inc.

Curated by ChEMBL


Assay Description
In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.


Bioorg Med Chem Lett 12: 1103-7 (2002)


BindingDB Entry DOI: 10.7270/Q2H131BN
More data for this
Ligand-Target Pair