BDBM50111414 3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-carbonyl)-piperidin-1-yl]-butyric acid::CHEMBL276482

SMILES: CC(CC(O)=O)N1CCC(CC1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1

InChI Key: InChIKey=IAGDYZSYUXWMJO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50111414 (3-[4-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-...) Show SMILES CC(CC(O)=O)N1CCC(CC1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1 Show InChI InChI=1S/C23H34N4O3/c1-18(16-21(28)29)25-11-4-19(5-12-25)22(30)26-13-6-23(7-14-26)8-15-27(17-23)20-2-9-24-10-3-20/h2-3,9-10,18-19H,4-8,11-17H2,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.				Bioorg Med Chem Lett 12: 1103-7 (2002) BindingDB Entry DOI: 10.7270/Q2H131BN
					More data for this Ligand-Target Pair