BDBM50111415 CHEMBL275967::[1-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-carbonyl)-piperidin-4-ylmethoxy]-acetic acid

SMILES: OC(=O)COCC1CCN(CC1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1

InChI Key: InChIKey=QFOOYMWYYFFGLA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50111415 (CHEMBL275967 | [1-(2-Pyridin-4-yl-2,8-diaza-spiro[...) Show SMILES OC(=O)COCC1CCN(CC1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1 Show InChI InChI=1S/C22H32N4O4/c27-20(28)16-30-15-18-3-10-24(11-4-18)21(29)25-12-5-22(6-13-25)7-14-26(17-22)19-1-8-23-9-2-19/h1-2,8-9,18H,3-7,10-17H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.				Bioorg Med Chem Lett 12: 1103-7 (2002) BindingDB Entry DOI: 10.7270/Q2H131BN
					More data for this Ligand-Target Pair