BDBM50111421 CHEMBL417800::[5-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-carbonyl)-indol-1-yl]-acetic acid

SMILES: OC(=O)Cn1ccc2cc(ccc12)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1

InChI Key: InChIKey=FVMOCQTUNDVKNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50111421 (CHEMBL417800 | [5-(2-Pyridin-4-yl-2,8-diaza-spiro[...) Show SMILES OC(=O)Cn1ccc2cc(ccc12)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1 Show InChI InChI=1S/C24H26N4O3/c29-22(30)16-27-11-5-18-15-19(1-2-21(18)27)23(31)26-12-6-24(7-13-26)8-14-28(17-24)20-3-9-25-10-4-20/h1-5,9-11,15H,6-8,12-14,16-17H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.				Bioorg Med Chem Lett 12: 1103-7 (2002) BindingDB Entry DOI: 10.7270/Q2H131BN
					More data for this Ligand-Target Pair