BDBM50111430 CHEMBL12953::[3-(2-Pyridin-4-yl-2,8-diaza-spiro[4.5]decane-8-carbonyl)-phenoxy]-acetic acid

SMILES: OC(=O)COc1cccc(c1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1

InChI Key: InChIKey=ZNOJLFJYJPAQFQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50111430 (CHEMBL12953 | [3-(2-Pyridin-4-yl-2,8-diaza-spiro[4...) Show SMILES OC(=O)COc1cccc(c1)C(=O)N1CCC2(CCN(C2)c2ccncc2)CC1 Show InChI InChI=1S/C22H25N3O4/c26-20(27)15-29-19-3-1-2-17(14-19)21(28)24-11-6-22(7-12-24)8-13-25(16-22)18-4-9-23-10-5-18/h1-5,9-10,14H,6-8,11-13,15-16H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	873	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description In vitro activity to block the binding of fibrinogen to purified human fibrinogen receptor.				Bioorg Med Chem Lett 12: 1103-7 (2002) BindingDB Entry DOI: 10.7270/Q2H131BN
					More data for this Ligand-Target Pair