BDBM50111435 7-Fluoro-1-methyl-9H-beta-carboline::CHEMBL14445

SMILES: Cc1nccc2c3ccc(F)cc3[nH]c12

InChI Key: InChIKey=DCEHWOIKAQDZGV-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50111435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3 (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of Cell division cycle 2 (CDK1)-cyclin B				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1 (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 2-cyclin A				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of protein kinase C				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of Fyn kinase				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of p56 Lck tyrosine kinase				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of Lyn tyrosine kinase				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50111435 (7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445) Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12 Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 5-p35nck5a				Bioorg Med Chem Lett 12: 1129-32 (2002) BindingDB Entry DOI: 10.7270/Q2CC1006
					More data for this Ligand-Target Pair