null

SMILES: Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)C1CC1

InChI Key: InChIKey=AQFMGFCVDBEMQE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50111575 (CHEMBL3603853) Show SMILES Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)C1CC1 Show InChI InChI=1S/C22H28IN7O2/c23-18-14-26-21(29-19(18)24-9-4-10-25-20(31)15-7-8-15)27-16-5-3-6-17(13-16)28-22(32)30-11-1-2-12-30/h3,5-6,13-15H,1-2,4,7-12H2,(H,25,31)(H,28,32)(H2,24,26,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 mins				Bioorg Med Chem 23: 5483-8 (2015) BindingDB Entry DOI: 10.7270/Q2CN75P8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK1 (Homo sapiens (Human))	BDBM50111575 (CHEMBL3603853) Show SMILES Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)C1CC1 Show InChI InChI=1S/C22H28IN7O2/c23-18-14-26-21(29-19(18)24-9-4-10-25-20(31)15-7-8-15)27-16-5-3-6-17(13-16)28-22(32)30-11-1-2-12-30/h3,5-6,13-15H,1-2,4,7-12H2,(H,25,31)(H,28,32)(H2,24,26,27,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) BindingDB Entry DOI: 10.7270/Q2CN75P8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK2 (Homo sapiens (Human))	BDBM50111575 (CHEMBL3603853) Show SMILES Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)C1CC1 Show InChI InChI=1S/C22H28IN7O2/c23-18-14-26-21(29-19(18)24-9-4-10-25-20(31)15-7-8-15)27-16-5-3-6-17(13-16)28-22(32)30-11-1-2-12-30/h3,5-6,13-15H,1-2,4,7-12H2,(H,25,31)(H,28,32)(H2,24,26,27,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) BindingDB Entry DOI: 10.7270/Q2CN75P8
					More data for this Ligand-Target Pair