null

SMILES: Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1nc(CN)cs1

InChI Key: InChIKey=WYQRAGPLMGNLNP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50111719 (CHEMBL19037 | N-(4-Aminomethyl-thiazol-2-ylmethyl)...) Show SMILES Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1nc(CN)cs1 Show InChI InChI=1S/C20H23N5O4S2/c1-14-7-8-17(24-31(28,29)13-15-5-3-2-4-6-15)20(27)25(14)11-18(26)22-10-19-23-16(9-21)12-30-19/h2-8,12,24H,9-11,13,21H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory constant against human thrombin (FIIa).				Bioorg Med Chem Lett 12: 1203-8 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FGB
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50111719 (CHEMBL19037 | N-(4-Aminomethyl-thiazol-2-ylmethyl)...) Show SMILES Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1nc(CN)cs1 Show InChI InChI=1S/C20H23N5O4S2/c1-14-7-8-17(24-31(28,29)13-15-5-3-2-4-6-15)20(27)25(14)11-18(26)22-10-19-23-16(9-21)12-30-19/h2-8,12,24H,9-11,13,21H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory constant against trypsin				Bioorg Med Chem Lett 12: 1203-8 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FGB
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50111719 (CHEMBL19037 | N-(4-Aminomethyl-thiazol-2-ylmethyl)...) Show SMILES Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1nc(CN)cs1 Show InChI InChI=1S/C20H23N5O4S2/c1-14-7-8-17(24-31(28,29)13-15-5-3-2-4-6-15)20(27)25(14)11-18(26)22-10-19-23-16(9-21)12-30-19/h2-8,12,24H,9-11,13,21H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>338	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory constant against factor Xa (FXa) was tested				Bioorg Med Chem Lett 12: 1203-8 (2002) BindingDB Entry DOI: 10.7270/Q2PK0FGB
					More data for this Ligand-Target Pair