BDBM50112028 1-[4-(1H-Imidazol-4-ylmethyl)-benzyl]-3-(3-trifluoromethyl-phenyl)-urea::CHEMBL173520
SMILES: FC(F)(F)c1cccc(NC(=O)NCc2ccc(Cc3cnc[nH]3)cc2)c1
InChI Key: InChIKey=PEAVWFVWMZUDSB-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histamine H3 receptor (GUINEA PIG) | BDBM50112028 (1-[4-(1H-Imidazol-4-ylmethyl)-benzyl]-3-(3-trifluo...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Schering Plough Research Institute Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membrane | Bioorg Med Chem Lett 12: 937-41 (2002) BindingDB Entry DOI: 10.7270/Q2W37VN7 | |||||||||||
More data for this Ligand-Target Pair |