BDBM50112212 1,1,1-trifluoro-2-bromo-2-chloroethane::1,1,1-trifluoro-2-chloro-2-bromoethane::1-bromo-1-chloro-2,2,2-trifluoroethane::2,2,2-trifluoro-1-chloro-1-bromoethane::2-bromo-2-chloro-1,1,1-trifluoroethane::CHEMBL931::Fluothane::HALOTHANE::Narcotane::Phthorothanum::Rhodialothan::bromochlorotrifluoroethane

SMILES: FC(F)(F)C(Cl)Br

InChI Key: InChIKey=BCQZXOMGPXTTIC-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serum albumin (Homo sapiens (Human))	BDBM50112212 (1,1,1-trifluoro-2-bromo-2-chloroethane | 1,1,1-tri...) Show SMILES FC(F)(F)C(Cl)Br Show InChI InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents	DrugBank PDB PubMed	n/a	n/a	2.90E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Health System Curated by ChEMBL					Assay Description Inhibitory concentration of the compound bound to tryptophan containing region of Serum albumin in fluorescence quenching				J Med Chem 45: 1879-86 (2002) BindingDB Entry DOI: 10.7270/Q2QF8S79
					More data for this Ligand-Target Pair				3D Structure (crystal)
Calcium channel (Type L) (Homo sapiens (Human))	BDBM50112212 (1,1,1-trifluoro-2-bromo-2-chloroethane | 1,1,1-tri...) Show SMILES FC(F)(F)C(Cl)Br Show InChI InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.45E+7	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in human embryonic kidney cells heterologically expressing alpha-1C sub...				J Appl Toxicol 32: 858-66 (2012) Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C
					More data for this Ligand-Target Pair
Calcium channel (Type L) (Homo sapiens (Human))	BDBM50112212 (1,1,1-trifluoro-2-bromo-2-chloroethane | 1,1,1-tri...) Show SMILES FC(F)(F)C(Cl)Br Show InChI InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.80E+6	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in human embryonic kidney cells heterologically expressing alpha-1C sub...				J Appl Toxicol 32: 858-66 (2012) Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C
					More data for this Ligand-Target Pair