BDBM50112229 5-(4-Methoxy-phenyl)-1-methyl-2-oxo-6-phenyl-1,2-dihydro-pyridine-3-carboxylic acid methyl ester::CHEMBL301195

SMILES: COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccccc2)n(C)c1=O

InChI Key: InChIKey=VDDATJOZLCYXHB-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50112229 (5-(4-Methoxy-phenyl)-1-methyl-2-oxo-6-phenyl-1,2-d...) Show SMILES COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccccc2)n(C)c1=O Show InChI InChI=1S/C21H19NO4/c1-22-19(15-7-5-4-6-8-15)17(13-18(20(22)23)21(24)26-3)14-9-11-16(25-2)12-10-14/h4-13H,1-3H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity by displacement of [3H]-Ro-15-1788 from recombinant human gamma-aminobutyric-acid A receptor alpha3,beta3,gamma2 stably expressed in...				J Med Chem 45: 1887-900 (2002) BindingDB Entry DOI: 10.7270/Q2KP81HZ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50112229 (5-(4-Methoxy-phenyl)-1-methyl-2-oxo-6-phenyl-1,2-d...) Show SMILES COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccccc2)n(C)c1=O Show InChI InChI=1S/C21H19NO4/c1-22-19(15-7-5-4-6-8-15)17(13-18(20(22)23)21(24)26-3)14-9-11-16(25-2)12-10-14/h4-13H,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 stably expressed in L(tk-) cells				J Med Chem 45: 1887-900 (2002) BindingDB Entry DOI: 10.7270/Q2KP81HZ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50112229 (5-(4-Methoxy-phenyl)-1-methyl-2-oxo-6-phenyl-1,2-d...) Show SMILES COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccccc2)n(C)c1=O Show InChI InChI=1S/C21H19NO4/c1-22-19(15-7-5-4-6-8-15)17(13-18(20(22)23)21(24)26-3)14-9-11-16(25-2)12-10-14/h4-13H,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro-15-1788 binding to human GABA A receptor (alpha5-beta3-gamma2) stably expressed in L(tk-) cells.				J Med Chem 45: 1887-900 (2002) BindingDB Entry DOI: 10.7270/Q2KP81HZ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50112229 (5-(4-Methoxy-phenyl)-1-methyl-2-oxo-6-phenyl-1,2-d...) Show SMILES COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccccc2)n(C)c1=O Show InChI InChI=1S/C21H19NO4/c1-22-19(15-7-5-4-6-8-15)17(13-18(20(22)23)21(24)26-3)14-9-11-16(25-2)12-10-14/h4-13H,1-3H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	625	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from human GABA-A receptor alpha1-beta3-gamma2 subunits expressed in L(tk-) cells				J Med Chem 45: 1887-900 (2002) BindingDB Entry DOI: 10.7270/Q2KP81HZ
					More data for this Ligand-Target Pair