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SMILES: CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccc(Cl)cc2OC(F)(F)F)cc1

InChI Key: InChIKey=KRJVKFMDNSDUEQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112359   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50112359
PNG
(CHEMBL3609415)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccc(Cl)cc2OC(F)(F)F)cc1
Show InChI InChI=1S/C23H18Cl2F3NO4S/c1-2-34(31,32)17-7-3-14(4-8-17)11-22(30)29-16-6-10-18(20(25)13-16)19-9-5-15(24)12-21(19)33-23(26,27)28/h3-10,12-13H,2,11H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
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UniChem

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PubMed
n/an/a 6.30n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of RORgammat (unknown origin) assessed as inhibition of agonist-induced response by FRET assay

ACS Med Chem Lett 6: 787-92 (2015)


BindingDB Entry DOI: 10.7270/Q2XG9SWD
More data for this
Ligand-Target Pair