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SMILES: CS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccc(Cl)cc2OC(F)(F)F)cc1

InChI Key: InChIKey=JSVDGUNSFOGAEG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112360   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50112360
PNG
(CHEMBL3609414)
Show SMILES CS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(Cl)c2)-c2ccc(Cl)cc2OC(F)(F)F)cc1
Show InChI InChI=1S/C22H16Cl2F3NO4S/c1-33(30,31)16-6-2-13(3-7-16)10-21(29)28-15-5-9-17(19(24)12-15)18-8-4-14(23)11-20(18)32-22(25,26)27/h2-9,11-12H,10H2,1H3,(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 7.90n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of RORgammat (unknown origin) assessed as inhibition of agonist-induced response by FRET assay

ACS Med Chem Lett 6: 787-92 (2015)


BindingDB Entry DOI: 10.7270/Q2XG9SWD
More data for this
Ligand-Target Pair