BDBM50112920 (2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quinoxalin-4-yl-amine::CHEMBL283212::N-(2-chloro-6-methylphenyl)imidazo[1,5-a]quinoxalin-4-amine

SMILES: Cc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12

InChI Key: InChIKey=FHXUGXXTIOXMKR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112920 ((2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quinoxali...) Show SMILES Cc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12 Show InChI InChI=1S/C17H13ClN4/c1-11-5-4-6-12(18)16(11)21-17-15-9-19-10-22(15)14-8-3-2-7-13(14)20-17/h2-10H,1H3,(H,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells using a baculovirus expression syst...				Bioorg Med Chem Lett 12: 1361-4 (2002) BindingDB Entry DOI: 10.7270/Q2R78DJ1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112920 ((2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quinoxali...) Show SMILES Cc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12 Show InChI InChI=1S/C17H13ClN4/c1-11-5-4-6-12(18)16(11)21-17-15-9-19-10-22(15)14-8-3-2-7-13(14)20-17/h2-10H,1H3,(H,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112920 ((2-Chloro-6-methyl-phenyl)-imidazo[1,5-a]quinoxali...) Show SMILES Cc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12 Show InChI InChI=1S/C17H13ClN4/c1-11-5-4-6-12(18)16(11)21-17-15-9-19-10-22(15)14-8-3-2-7-13(14)20-17/h2-10H,1H3,(H,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Evaluated for inhibition of human p56 Lck tyrosine kinase				J Med Chem 47: 2534-49 (2004) Article DOI: 10.1021/jm0304358 BindingDB Entry DOI: 10.7270/Q2KH0P3P
					More data for this Ligand-Target Pair