BDBM50113020 (2R,4S)-1-[4-(Biphenyl-2-ylmethoxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL282094

SMILES: ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2-c2ccccc2)cc1

InChI Key: InChIKey=HLNRKJGRBAIQKZ-GBXCKJPGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50113020 ((2R,4S)-1-[4-(Biphenyl-2-ylmethoxy)-benzenesulfony...) Show SMILES ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2-c2ccccc2)cc1 Show InChI InChI=1S/C25H26N2O6S/c28-20-14-15-27(24(16-20)25(29)26-30)34(31,32)22-12-10-21(11-13-22)33-17-19-8-4-5-9-23(19)18-6-2-1-3-7-18/h1-13,20,24,28,30H,14-17H2,(H,26,29)/t20-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme				Bioorg Med Chem Lett 12: 1387-90 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X30
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50113020 ((2R,4S)-1-[4-(Biphenyl-2-ylmethoxy)-benzenesulfony...) Show SMILES ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2-c2ccccc2)cc1 Show InChI InChI=1S/C25H26N2O6S/c28-20-14-15-27(24(16-20)25(29)26-30)34(31,32)22-12-10-21(11-13-22)33-17-19-8-4-5-9-23(19)18-6-2-1-3-7-18/h1-13,20,24,28,30H,14-17H2,(H,26,29)/t20-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme				Bioorg Med Chem Lett 12: 1387-90 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X30
					More data for this Ligand-Target Pair