BDBM50113025 (2R,5R)-5-Hydroxy-1-[4-(naphthalen-1-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31315

SMILES: ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1

InChI Key: InChIKey=FYZJGFHMVNBOIV-XMSQKQJNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50113025 ((2R,5R)-5-Hydroxy-1-[4-(naphthalen-1-ylmethoxy)-be...) Show SMILES ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C23H24N2O6S/c26-18-8-13-22(23(27)24-28)25(14-18)32(29,30)20-11-9-19(10-12-20)31-15-17-6-3-5-16-4-1-2-7-21(16)17/h1-7,9-12,18,22,26,28H,8,13-15H2,(H,24,27)/t18-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme				Bioorg Med Chem Lett 12: 1387-90 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X30
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50113025 ((2R,5R)-5-Hydroxy-1-[4-(naphthalen-1-ylmethoxy)-be...) Show SMILES ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C23H24N2O6S/c26-18-8-13-22(23(27)24-28)25(14-18)32(29,30)20-11-9-19(10-12-20)31-15-17-6-3-5-16-4-1-2-7-21(16)17/h1-7,9-12,18,22,26,28H,8,13-15H2,(H,24,27)/t18-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay				Bioorg Med Chem Lett 12: 1387-90 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X30
					More data for this Ligand-Target Pair