BDBM50113054 (E)-3-Methyl-5-naphthalen-2-yl-pent-2-en-1-diphosphate

SMILES: C\C(CCc1ccc2ccccc2c1)=C/COP([O-])(=O)OP([O-])([O-])=O

InChI Key: InChIKey=ICDHXOKCDDFYNH-JLHYYAGUSA-K

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50113054 ((E)-3-Methyl-5-naphthalen-2-yl-pent-2-en-1-diphosp...) Show SMILES C\C(CCc1ccc2ccccc2c1)=C/COP([O-])(=O)OP([O-])([O-])=O Show InChI InChI=1S/C16H20O7P2/c1-13(10-11-22-25(20,21)23-24(17,18)19)6-7-14-8-9-15-4-2-3-5-16(15)12-14/h2-5,8-10,12H,6-7,11H2,1H3,(H,20,21)(H2,17,18,19)/p-3/b13-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibitory activity against mammalian protein-Farnesyltransferase				Bioorg Med Chem Lett 12: 1417-20 (2002) BindingDB Entry DOI: 10.7270/Q2QF8TDZ
					More data for this Ligand-Target Pair